Cholesterol Degradation by Gordonia cholesterolivorans

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Cholesterol degradation by Gordonia cholesterolivorans.

This paper reports physiological and genetic data about the type strain Gordonia cholesterolivorans, a strain that is able to degrade steroid compounds containing a long carbon side chain such as cholesterol (C(27)), cholestenone (C(27)), ergosterol (C(28)), and stigmasterol (C(29)). The length of the carbon side chain appears to be of great importance for this bacterium, as the strain is unabl...

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microbial chain degradation of cholesterol by arthrob acter simplex

because of the importance of microbial metabolites of cholesterol as precursors in the synthesis of steroidal drugs, we decided to study the ability of arthrobacter simplex to degrade cholesterol. arthrobacter simplex cleaves the side chain of cholesterol in the presence of 2,2'-dipyridyl and produces 4-androstene-3,17- dione (ad) and androsta- 1,4-diene-3,17-dione(add). two other intermed...

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 2011

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.05149-11